ANXA2P2

Across TCGA pan-cancer cohorts, ANXA2P2 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ANXA2P2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ANXA2P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANXA2P2 is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

KIRP, COAD, and LIHC are the cancer types where ANXA2P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANXA2P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+1.451	<.001	11	view →
COAD	All	III,IV	+1.179	<.001	11	view →
LIHC	Male	II,III,IV	+1.574	<.001	9	view →
KIRC	Male	All	+0.780	<.001	9	view →
CHOL	Male	All	+3.096	<.001	5	view →
HNSC	Male	All	+0.658	.001	5	view →
KICH	Female	All	−1.339	<.001	4	view →
THCA	Male	III,IV	+0.932	.002	4	view →
STAD	All	All	+0.776	.017	3	view →
PRAD	All	All	−1.047	<.001	2	view →
READ	All	III,IV	+0.994	.047	2	view →
BLCA	All	IV	+0.902	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ANXA2P2–KIRP

Open the KIRP breakdown →