ANXA2

Across TCGA patient cohorts, ANXA2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,727 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANXA2-associated genes across cancer lineages are EMP1, TMBIM1, and CAST. Each is linked with ANXA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANXA2-to-partner and partner-to-ANXA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANXA2 versus EMP1 in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA2→partner) and Y-score (partner→ANXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EMP1 →	+1.163	+0.746	<.001	<.001	3	8
UCEC	TMBIM1 →	+0.610	+0.370	.002	.003	3	7
BRCA	CAST →	+0.597	+0.326	<.001	.001	3	7
HNSC	ALS2CL →	+1.069	+0.420	<.001	<.001	3	7
OV	AHNAK2 →	+1.621	+0.438	<.001	.002	3	7
PDAC	KRT16 →	+2.018	+0.275	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,727 associations by consensus.

ANXA2 vs EMP1 — GBM

Explore this scatter interactively →