ANXA2

Across TCGA patient cohorts, ANXA2 mutation is significantly associated with the RNA expression of many other genes, with 279 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA2-associated genes across cancer lineages are RN7SKP204, OR7G15P, and RPL7AP69. Each is linked with ANXA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANXA2-to-partner and partner-to-ANXA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP204 grouped by ANXA2-low versus ANXA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA2→partner) and Y-score (partner→ANXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP204 →	+0.229	+2.661	.007	.006	3	3
BLCA	OR7G15P →	+0.144	+5.177	<.001	.007	3	2
CESC	RPL7AP69 →	+0.057	+5.010	<.001	.009	3	2
UCEC	PGAP2 →	+0.434	+3.711	.009	<.001	3	1
UCEC	GRIK4 →	-0.512	-3.700	.009	.001	3	1
UCEC	FAM177A1 →	+0.505	+3.711	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 279 associations by consensus.

RN7SKP204 by ANXA2 expression — UCEC

Explore this box plot interactively →