ANXA2

Across TCGA cell cohorts, ANXA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,015 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ANXA2-associated GO terms across cancer lineages are Regulation of plasminogen activation, Regulation of plasma membrane repair, and Positive regulation of plasma membrane repair. Each is linked with ANXA2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ANXA2-to-partner and partner-to-ANXA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasminogen activation grouped by ANXA2-low versus ANXA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA2→partner) and Y-score (partner→ANXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of plasminogen activation →	+0.299	+1.680	<.001	<.001	3	16
BONE	Regulation of plasma membrane repair →	+0.420	+1.776	<.001	<.001	3	16
LUNG_SCLC	Positive regulation of plasma membrane repair →	+0.495	+2.670	<.001	<.001	3	16
LIVER	Cellular response to abiotic stimulus →	+0.053	+1.402	.001	.001	3	15
LIVER	Cellular response to environmental stimulus →	+0.053	+1.402	.001	.001	3	15
BONE	Positive regulation of protein maturation →	+0.211	+1.859	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,015 associations by consensus.

Regulation of plasminogen activation by ANXA2 expression — BONE

Explore this box plot interactively →