ANXA13

Across TCGA patient cohorts, ANXA13 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA13-associated genes across cancer lineages are Cyclin-B1, 14-3-3_beta, and INPP4B. Each is linked with ANXA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA13-to-partner and partner-to-ANXA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by ANXA13-low versus ANXA13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA13→partner) and Y-score (partner→ANXA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.510	+1.807	.028	.027	3	2
UCEC	14-3-3_beta →	-0.110	-2.973	.008	.035	3	1
UCEC	INPP4B →	-0.283	-3.169	.034	.018	3	1
UCEC	JNK2 →	+0.231	+1.807	.004	.027	3	1
UCEC	Ku80 →	+0.219	+1.820	.024	.016	3	1
UCEC	MSH6 →	-0.416	-2.321	.002	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Cyclin-B1 by ANXA13 expression — UCEC

Explore this box plot interactively →