ANXA13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA13 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANXA13-associated genes across cancer lineages are ZIC3, HRG, and LRCH2. Each is linked with ANXA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA13-to-partner and partner-to-ANXA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZIC3 grouped by ANXA13-low versus ANXA13-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA13→partner) and Y-score (partner→ANXA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaZIC3 →+0.015+4.060<.001.00332
BLOOD_LeukemiaHRG →+0.349+3.855<.001.00731
BLOOD_LeukemiaLRCH2 →+0.581+3.807<.001.00731
BLOOD_LeukemiaZPBP2 →+0.604+3.777<.001.00831
BLOOD_LeukemiaCYP4A11 →+0.025+3.705<.001.00731
BLOOD_LeukemiaTMEM244 →+0.271+3.551<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ZIC3 by ANXA13 expression — BLOOD_Leukemia

Box plot of ZIC3 in ANXA13-low vs ANXA13-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration