ANXA11

Across TCGA patient cohorts, ANXA11 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA11-associated genes across cancer lineages are GAPDH, JNK2, and MEK1. Each is linked with ANXA11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA11-to-partner and partner-to-ANXA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by ANXA11-low versus ANXA11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA11→partner) and Y-score (partner→ANXA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.383	+1.807	.039	.024	3	2
COAD	JNK2 →	+0.242	+2.815	.017	.036	3	2
UCEC	MEK1 →	+0.499	+3.087	<.001	<.001	3	2
UCEC	Notch1 →	+0.162	+3.916	<.001	<.001	3	2
UCEC	p21 →	+0.149	+2.584	.025	.010	3	2
UCEC	Shc_pY317 →	-0.130	-1.874	.013	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

GAPDH by ANXA11 expression — UCEC

Explore this box plot interactively →