ANXA11

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA11 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANXA11-associated genes across cancer lineages are NPFFR1, DCLK3, and CTRB2. Each is linked with ANXA11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA11-to-partner and partner-to-ANXA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPFFR1 grouped by ANXA11-low versus ANXA11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA11→partner) and Y-score (partner→ANXA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaNPFFR1 →+0.015+4.037<.001.00431
BLOOD_LeukemiaDCLK3 →+0.214+3.769<.001.00831
BLOOD_LeukemiaCTRB2 →+0.095+3.855<.001.00731
BLOOD_LeukemiaMRGPRD →+0.646+3.855<.001.00731
BLOOD_LeukemiaOR10K1 →+0.504+4.234<.001.00331
BLOOD_LeukemiaKLK15 →+0.536+3.769<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

NPFFR1 by ANXA11 expression — BLOOD_Leukemia

Box plot of NPFFR1 in ANXA11-low vs ANXA11-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration