ANXA1

Across TCGA patient cohorts, ANXA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,650 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANXA1-associated proteins across cancer lineages are ANXA1_S173, NIBAN2, and NIBAN2_S692. Each is linked with ANXA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANXA1-to-partner and partner-to-ANXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANXA1 versus ANXA1_S173 in BRCA, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA1→partner) and Y-score (partner→ANXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANXA1_S173 →	+1.153	+1.115	<.001	<.001	3	8
OV	NIBAN2 →	+0.544	+1.453	<.001	<.001	3	7
LUAD	NIBAN2_S692 →	+0.585	+1.051	<.001	<.001	3	7
BRCA	EHBP1_S1058 →	+0.501	+0.678	<.001	<.001	3	7
UCEC	ANXA1_Y39 →	+1.346	+2.203	<.001	<.001	3	7
GBM	MYO1E →	+0.310	+0.918	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,650 associations by consensus.

ANXA1 vs ANXA1_S173 — BRCA

Explore this scatter interactively →