ANXA1

Across TCGA patient cohorts, ANXA1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,010 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ANXA1-associated genes across cancer lineages are ANXA2, KRT16, and TMBIM1. Each is linked with ANXA1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ANXA1-to-partner and partner-to-ANXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANXA1 versus ANXA2 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA1→partner) and Y-score (partner→ANXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANXA2 →	+0.953	+0.637	<.001	<.001	3	9
HNSC	KRT16 →	+1.644	+0.484	<.001	<.001	3	8
HNSC	TMBIM1 →	+0.807	+0.827	<.001	<.001	3	7
UCEC	MILR1 →	+0.911	+0.562	.001	.002	3	7
GBM	GNA15 →	+0.952	+0.671	<.001	<.001	3	7
UCEC	DAPP1 →	+1.030	+0.671	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,010 associations by consensus.

ANXA1 vs ANXA2 — UCEC

Explore this scatter interactively →