ANTXRL

Across TCGA cell cohorts, ANTXRL mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ANTXRL-associated genes across cancer lineages are DEFB124, TFAP2D, and LGALS13. Each is linked with ANTXRL in more than 1 cancer types. Because this analysis shows association rather than direction, both ANTXRL-to-partner and partner-to-ANTXRL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB124 grouped by ANTXRL-low versus ANTXRL-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANTXRL→partner) and Y-score (partner→ANTXRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DEFB124 →	+0.187	+4.108	<.001	.005	3	1
SOFT_TISSUE	TFAP2D →	+0.022	+4.930	<.001	.008	3	1
OESOPHAGUS	LGALS13 →	+0.073	+4.906	<.001	.006	3	1
OESOPHAGUS	FSCB →	+0.046	+4.906	<.001	.006	3	1
LARGE_INTESTINE	GCM2 →	+0.080	+3.920	<.001	.005	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.156	+4.108	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

DEFB124 by ANTXRL expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →