ANTXR1

Across TCGA pan-cancer cohorts, ANTXR1 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated ANTXR1 data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ANTXR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ANTXR1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BRCA, HNSC, and UCEC are the cancer types where ANTXR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.599	0.924	<.001	34	view →
HNSC	DFS	Median	All	0.078	0.710	<.001	24	view →
UCEC	OS	Median	All	0.968	0.656	.020	14	view →
LGG	OS	Median	All	0.177	0.909	<.001	12	view →
LUAD	DFS	Median	All	0.430	0.772	.005	8	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
COAD	DFS	Median	All	0.108	0.568	<.001	6	view →
SKCM	DFS	Median	All	0.192	0.757	.022	6	view →
READ	DFS	Median	All	0.149	0.583	.036	5	view →
LIHC	OS	Median	All	0.105	0.774	.002	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

ANTXR1–BRCA (OS)

Open the BRCA breakdown →