ANTXR1

Across TCGA pan-cancer cohorts, ANTXR1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ANTXR1 data layer compared with 23 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ANTXR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANTXR1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

LSCC, PDAC, and HNSC are the cancer types where ANTXR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.507	0.862	.002	24	view →
PDAC	DFS	Quartile	III,IV	0.227	0.875	.006	19	view →
HNSC	DFS	Tertile	II,III,IV	0.889	0.755	.016	10	view →
GBM	DFS	Quartile	All	0.536	0.305	.026	4	view →
CCRCC	DFS	Quartile	II,III,IV	0.774	0.323	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ANTXR1–LSCC (DFS)

Open the LSCC breakdown →