ANPEP

Across TCGA patient cohorts, ANPEP RNA expression is significantly associated with the protein abundance of many other proteins, with 20,447 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANPEP-associated proteins across cancer lineages are TLR2, VIM_S22, and CRISPLD2. Each is linked with ANPEP in more than 4 cancer types. Because this analysis shows association rather than direction, both ANPEP-to-partner and partner-to-ANPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANPEP versus TLR2 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANPEP→partner) and Y-score (partner→ANPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLR2 →	+0.606	+1.286	<.001	<.001	3	5
OV	VIM_S22 →	+0.843	+1.332	.001	.001	3	5
GBM	CRISPLD2 →	+0.876	+1.096	<.001	<.001	3	5
GBM	DAB2 →	+0.792	+1.336	<.001	<.001	3	5
OV	FAP →	+0.919	+1.438	.002	<.001	3	5
GBM	PCOLCE →	+0.665	+0.990	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,447 associations by consensus.

ANPEP vs TLR2 — GBM

Explore this scatter interactively →