ANPEP

Across TCGA patient cohorts, ANPEP protein abundance is significantly associated with the RNA expression of many other genes, with 14,398 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANPEP-associated genes across cancer lineages are ADAM12, CALHM5, and COL6A2. Each is linked with ANPEP in more than 5 cancer types. Because this analysis shows association rather than direction, both ANPEP-to-partner and partner-to-ANPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANPEP versus ADAM12 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANPEP→partner) and Y-score (partner→ANPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADAM12 →	+1.781	+0.748	<.001	.001	3	6
OV	CALHM5 →	+0.534	+0.596	.009	.003	3	6
OV	COL6A2 →	+1.587	+0.731	.001	.001	3	6
OV	RCN3 →	+1.593	+0.887	<.001	<.001	3	6
OV	COL3A1 →	+2.405	+0.802	<.001	.001	3	6
GBM	COL1A1 →	+2.282	+0.856	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,398 associations by consensus.

ANPEP vs ADAM12 — OV

Explore this scatter interactively →