ANP32BP3

Across TCGA pan-cancer cohorts, ANP32BP3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ANP32BP3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ANP32BP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANP32BP3 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

COAD, THCA, and LUSC are the cancer types where ANP32BP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANP32BP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.160	.001	7	view →
THCA	Male	All	−0.074	.003	3	view →
LUSC	All	All	+0.069	.022	1	view →
KIRP	Male	All	−0.035	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ANP32BP3–COAD

Open the COAD breakdown →