ANP32BP2

Across TCGA pan-cancer cohorts, ANP32BP2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ANP32BP2’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ANP32BP2 RNA is repressed in tumor relative to normal tissue. In most cancer types ANP32BP2 is over-expressed in tumor, although a few such as BLCA and BRCA show the opposite, repressed pattern.

BLCA, BRCA, and HNSC are the cancer types where ANP32BP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANP32BP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−0.112	.003	8	view →
BRCA	All	All	−0.065	<.001	6	view →
HNSC	All	All	+0.069	.030	2	view →
KIRC	All	All	+0.020	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ANP32BP2–BLCA

Open the BLCA breakdown →