ANP32BP1

Across TCGA pan-cancer cohorts, ANP32BP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ANP32BP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ANP32BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANP32BP1 is over-expressed in tumor.

HNSC, COAD, and LIHC are the cancer types where ANP32BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANP32BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.160	<.001	9	view →
COAD	All	II,III,IV	+0.514	<.001	8	view →
LIHC	All	II,III,IV	+0.075	<.001	5	view →
KIRC	Male	All	+0.048	.020	2	view →
READ	All	All	+0.173	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ANP32BP1–HNSC

Open the HNSC breakdown →