ANP32B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANP32B mutation is significantly associated with the RNA expression of many other genes, with 928 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANP32B-associated genes across cancer lineages are LINC01758, USP9YP2, and MIR6803. Each is linked with ANP32B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32B-to-partner and partner-to-ANP32B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01758 grouped by ANP32B-low versus ANP32B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32B→partner) and Y-score (partner→ANP32B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC01758 →+0.155+2.356<.001.00132
UCECUSP9YP2 →+0.016+4.978<.001.00132
UCECMIR6803 →+0.205+5.063<.001<.00131
UCECSNX3P1Y →+0.093+4.390<.001.00331
UCECLIN7C →+0.504+1.928.009.00931
UCECPGAP2 →+0.386+3.502.007.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 928 associations by consensus.

LINC01758 by ANP32B expression — UCEC

Box plot of LINC01758 in ANP32B-low vs ANP32B-high samples in UCEC.

Explore this box plot interactively →

Exploration