ANP32B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANP32B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,061 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANP32B-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Positive regulation of chromosome condensation, and Attachment of mitotic spindle microtubules to kinetochore. Each is linked with ANP32B in more than 17 cancer types. Because this analysis shows association rather than direction, both ANP32B-to-partner and partner-to-ANP32B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by ANP32B-low versus ANP32B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32B→partner) and Y-score (partner→ANP32B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASImmunoglobulin heavy chain V-D-J recombination →+0.235+1.083<.001<.001318
PANCREASPositive regulation of chromosome condensation →+0.229+0.857<.001<.001316
BREASTAttachment of mitotic spindle microtubules to kinetochore →+0.128+0.632<.001.002315
BREASTRegulation of chromosome condensation →+0.176+0.622<.001.004315
PANCREASDNA replication initiation →+0.205+0.944<.001<.001315
UPPER_AERODIGESTIVE_TRACTSomatic cell DNA recombination →+0.096+0.666<.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,061 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by ANP32B expression — PANCREAS

Box plot of Immunoglobulin heavy chain V-D-J recombination in ANP32B-low vs ANP32B-high samples in PANCREAS.

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Exploration