ANOS2P

Across TCGA pan-cancer cohorts, ANOS2P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ANOS2P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ANOS2P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ANOS2P expression acts as an unfavorable survival marker, although some lineages such as HNSC and UVM show a favorable association.

HNSC, UVM, and DLBC are the cancer types where ANOS2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.498	0.254	.001	69	view →
UVM	DFS	Tertile	III,IV	0.954	0.553	.008	61	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	30	view →
SKCM	DFS	Tertile	All	0.359	0.769	<.001	27	view →
LUAD	DFS	Median	IV	0.847	0.522	.011	18	view →
ACC	OS	Tertile	All	0.214	0.820	.006	18	view →
MESO	OS	Tertile	III,IV	0.153	0.590	.010	15	view →
PAAD	DFS	Median	III,IV	0.893	0.470	.024	13	view →
BLCA	OS	Quartile	III,IV	0.731	0.559	.003	13	view →
ESCA	DFS	Tertile	III,IV	0.531	0.307	.013	11	view →
CHOL	OS	Quartile	III,IV	0.138	0.786	.017	9	view →
PCPG	OS	Quartile	All	0.909	0.988	.026	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ANOS2P–HNSC (DFS)

Open the HNSC breakdown →