ANOS1

Across TCGA patient cohorts, ANOS1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,705 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ANOS1-associated genes across cancer lineages are RAB23, FBN1, and INHBA. Each is linked with ANOS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANOS1-to-partner and partner-to-ANOS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANOS1 versus RAB23 in CCRCC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANOS1→partner) and Y-score (partner→ANOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RAB23 →	+0.600	+0.953	.002	.003	3	6
BRCA	FBN1 →	+1.299	+0.650	<.001	<.001	3	5
BRCA	INHBA →	+0.994	+0.637	<.001	<.001	3	4
GBM	ADAMTS12 →	+0.867	+0.427	.001	.001	3	4
HNSC	SYNDIG1 →	+0.978	+0.524	.003	.003	3	4
LUAD	COL12A1 →	+1.471	+0.312	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,705 associations by consensus.

ANOS1 vs RAB23 — CCRCC

Explore this scatter interactively →