ANOS1

Across TCGA cell cohorts, ANOS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,306 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ANOS1-associated GO terms across cancer lineages are Protein stabilization, Negative regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ANOS1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ANOS1-to-partner and partner-to-ANOS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by ANOS1-low versus ANOS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANOS1→partner) and Y-score (partner→ANOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein stabilization →	+0.064	+1.924	<.001	<.001	3	10
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.110	+0.170	<.001	.007	3	10
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.089	+0.181	<.001	.004	3	10
BONE	Golgi vesicle transport →	+0.069	+1.886	<.001	.002	3	9
STOMACH	Post-embryonic eye morphogenesis →	+0.875	+1.550	.004	.001	3	9
LUNG_SCLC	Vesicle coating →	+0.064	+1.493	.006	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,306 associations by consensus.

Protein stabilization by ANOS1 expression — BONE

Explore this box plot interactively →