Across TCGA patient cohorts, ANO9 mutation is significantly associated with the RNA expression of many other genes, with 1,399 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANO9-associated genes across cancer lineages are DEFB112, RNA5SP190, and LCE2A. Each is linked with ANO9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANO9-to-partner and partner-to-ANO9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO9→partner) and Y-score (partner→ANO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DEFB112 →	+0.070	+4.936	<.001	.003	3	2
HNSC	RNA5SP190 →	+0.326	+4.009	.001	.001	3	2
LGG	LCE2A →	+0.050	+4.660	<.001	.005	3	2
LGG	TRDV1 →	+0.262	+4.522	<.001	.001	3	2
LGG	RN7SL299P →	+0.088	+4.351	.002	.008	3	2
LGG	OR5D15P →	+0.144	+4.778	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,399 associations by consensus.

Exploration

ANO9 survival (RNA) · tumor vs normal (RNA) · all ANO9 data types