Across TCGA cell cohorts, ANO9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANO9-associated genes across cancer lineages are MAGEB4, PTH, and C8A. Each is linked with ANO9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANO9-to-partner and partner-to-ANO9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO9→partner) and Y-score (partner→ANO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	1
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	C8A →	+0.026	+3.684	<.001	.006	3	1
LARGE_INTESTINE	PRR27 →	+0.215	+4.054	<.001	.004	3	1
OVARY	C1QTNF7 →	+0.507	+3.657	<.001	.009	3	1
OVARY	C1orf146 →	+0.053	+4.865	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ANO9 survival (RNA) · tumor vs normal (RNA) · all ANO9 data types