ANO7

Across TCGA cell cohorts, ANO7 mutation is significantly associated with the RNA expression of many other genes, with 501 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANO7-associated genes across cancer lineages are DYNAP, NEUROD6, and RNASE8. Each is linked with ANO7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANO7-to-partner and partner-to-ANO7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYNAP grouped by ANO7-low versus ANO7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO7→partner) and Y-score (partner→ANO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DYNAP →	+0.075	+3.196	<.001	.007	3	2
URINARY_TRACT	NEUROD6 →	+0.022	+4.087	<.001	.009	3	1
URINARY_TRACT	RNASE8 →	+0.045	+4.584	<.001	.002	3	1
URINARY_TRACT	OR4F15 →	+0.144	+4.217	<.001	.005	3	1
URINARY_TRACT	SKOR2 →	+0.037	+4.087	.001	.009	3	1
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 501 associations by consensus.

DYNAP by ANO7 expression — SKIN

Explore this box plot interactively →