ANO3-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ANO3-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated ANO3-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ANO3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANO3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LIHC show a favorable association.

ACC, COAD, and HNSC are the cancer types where ANO3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSTertileAll0.0100.667<.001135view →
COADOSTertileAll0.4080.805<.001108view →
HNSCDFSTertileAll0.1830.667<.00175view →
KIRPOSTertileAll0.8030.943<.00169view →
SKCMOSTertileII,III,IV0.0950.370.00557view →
LUADOSTertileIII,IV0.0700.693<.00145view →
STADDFSTertileAll0.1960.595.02736view →
ESCAOSTertileIV0.0950.512.00836view →
THCADFSTertileIII,IV0.7830.943.00524view →
SARCDFSTertileAll0.2440.603.00818view →
LUSCOSTertileII,III,IV0.1330.732<.00118view →
KIRCOSTertileAll0.4570.672.00712view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

ANO3-AS1–ACC (DFS)

Kaplan–Meier survival curve for ANO3-AS1 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration