ANO2

Across TCGA cell cohorts, ANO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,027 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ANO2-associated GO terms across cancer lineages are Neurotransmitter transport, Signal release from synapse, and Action potential. Each is linked with ANO2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANO2-to-partner and partner-to-ANO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neurotransmitter transport grouped by ANO2-low versus ANO2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO2→partner) and Y-score (partner→ANO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Neurotransmitter transport →	-0.083	-1.137	<.001	<.001	3	8
BONE	Signal release from synapse →	-0.085	-1.486	<.001	.002	3	7
OVARY	Action potential →	-0.077	-1.363	<.001	<.001	3	7
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.057	+0.542	<.001	.003	3	7
BONE	Golgi to plasma membrane protein transport →	+0.117	+1.158	<.001	<.001	3	7
BONE	Neurotransmitter secretion →	-0.085	-1.486	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,027 associations by consensus.

Neurotransmitter transport by ANO2 expression — BONE

Explore this box plot interactively →