ANO10

Across TCGA pan-cancer cohorts, ANO10 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ANO10 data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ANO10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ANO10 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

COAD, LUAD, and GBM are the cancer types where ANO10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.012	42	view →
LUAD	DFS	Median	All	0.632	0.950	.002	32	view →
GBM	OS	Tertile	All	0.338	0.605	.001	20	view →
CCRCC	DFS	Tertile	II,III,IV	0.166	0.790	.035	5	view →
LSCC	DFS	Tertile	II,III,IV	0.824	1.000	.039	2	view →
PDAC	OS	Tertile	III,IV	0.714	0.988	.020	2	view →
HNSC	OS	Quartile	All	0.968	0.859	.031	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ANO10–COAD (DFS)

Open the COAD breakdown →