ANO10

Across TCGA cell cohorts, ANO10 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANO10-associated genes across cancer lineages are MYOD1, NKX2-6, and TLE7. Each is linked with ANO10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANO10-to-partner and partner-to-ANO10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by ANO10-low versus ANO10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO10→partner) and Y-score (partner→ANO10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYOD1 →	+0.022	+4.922	<.001	.009	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
LARGE_INTESTINE	FMO1 →	+0.136	+3.099	<.001	.004	3	1
LARGE_INTESTINE	ACADL →	+0.606	+3.333	<.001	.009	3	1
LARGE_INTESTINE	A4GNT →	+0.084	+4.029	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

MYOD1 by ANO10 expression — BLOOD_Leukemia

Explore this box plot interactively →