ANO1

Across TCGA patient cohorts, ANO1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,914 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ANO1-associated genes across cancer lineages are LINC02584, LINC02753, and AFAP1L2. Each is linked with ANO1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ANO1-to-partner and partner-to-ANO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANO1 versus LINC02584 in PDAC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO1→partner) and Y-score (partner→ANO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LINC02584 →	+0.894	+0.445	<.001	<.001	3	7
PDAC	LINC02753 →	+0.747	+0.459	<.001	<.001	3	6
LUAD	AFAP1L2 →	+1.240	+0.605	<.001	<.001	3	5
CCRCC	RHOJ →	+0.763	+0.429	<.001	<.001	3	4
OV	C3orf70 →	+0.757	+1.005	.001	.005	3	4
BRCA	FRMD6 →	+1.046	+0.582	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,914 associations by consensus.

ANO1 vs LINC02584 — PDAC

Explore this scatter interactively →