ANO1

Across TCGA cell cohorts, ANO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,934 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ANO1-associated GO terms across cancer lineages are Trachea development, Sodium ion homeostasis, and Regulation of potassium ion import. Each is linked with ANO1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ANO1-to-partner and partner-to-ANO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Trachea development grouped by ANO1-low versus ANO1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO1→partner) and Y-score (partner→ANO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Trachea development →	+1.279	+1.249	.001	.001	3	11
STOMACH	Sodium ion homeostasis →	+0.240	+3.075	<.001	<.001	3	10
STOMACH	Regulation of potassium ion import →	+0.212	+2.626	<.001	<.001	3	10
STOMACH	NMDA selective glutamate receptor signaling pathway →	+0.249	+2.795	.001	.002	3	9
STOMACH	Intracellular sodium ion homeostasis →	+0.270	+3.370	<.001	<.001	3	9
OVARY	Nail development →	+0.508	+2.037	.004	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,934 associations by consensus.

Trachea development by ANO1 expression — BONE

Explore this box plot interactively →