ANLN

Across TCGA patient cohorts, ANLN mutation is significantly associated with the RNA expression of many other genes, with 5,062 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANLN-associated genes across cancer lineages are LINC02871, RPL12P24, and OR2M2. Each is linked with ANLN in more than 2 cancer types. Because this analysis shows association rather than direction, both ANLN-to-partner and partner-to-ANLN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02871 grouped by ANLN-low versus ANLN-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANLN→partner) and Y-score (partner→ANLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02871 →	+0.064	+4.051	.008	.001	3	3
COAD	RPL12P24 →	+0.377	+4.958	<.001	<.001	3	3
SKCM	OR2M2 →	+0.025	+2.628	<.001	.005	3	3
SKCM	SERBP1 →	+0.501	+3.182	.004	.009	3	3
SKCM	RAB10 →	+0.511	+2.517	.002	.009	3	3
UCEC	SC5D →	+0.407	+1.962	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,062 associations by consensus.

LINC02871 by ANLN expression — BLCA

Explore this box plot interactively →