ANLN

Across TCGA cell cohorts, ANLN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,000 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ANLN-associated GO terms across cancer lineages are Mitotic metaphase chromosome alignment, Negative regulation of metaphase/anaphase transition of cell cycle, and Negative regulation of chromosome separation. Each is linked with ANLN in more than 18 cancer types. Because this analysis shows association rather than direction, both ANLN-to-partner and partner-to-ANLN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic metaphase chromosome alignment grouped by ANLN-low versus ANLN-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANLN→partner) and Y-score (partner→ANLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic metaphase chromosome alignment →	+0.116	+1.552	.001	.002	3	19
URINARY_TRACT	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.171	+1.554	<.001	<.001	3	19
URINARY_TRACT	Negative regulation of chromosome separation →	+0.171	+1.554	<.001	<.001	3	19
BONE	Negative regulation of nuclear division →	+0.176	+1.599	.007	.003	3	18
URINARY_TRACT	Negative regulation of mitotic sister chromatid separation →	+0.196	+1.538	<.001	<.001	3	18
KIDNEY	Mitotic spindle elongation →	+0.272	+1.595	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,000 associations by consensus.

Mitotic metaphase chromosome alignment by ANLN expression — OESOPHAGUS

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