ANKZF1

Across TCGA patient cohorts, ANKZF1 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKZF1-associated genes across cancer lineages are eEF2, mTOR_pS2448, and Tuberin_pT1462. Each is linked with ANKZF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKZF1-to-partner and partner-to-ANKZF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ANKZF1-low versus ANKZF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKZF1→partner) and Y-score (partner→ANKZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.292	+2.807	.016	.002	3	2
UCEC	mTOR_pS2448 →	-0.123	-1.514	.015	.015	3	2
UCEC	Tuberin_pT1462 →	+0.230	+1.290	.003	.034	3	2
UCEC	ATM →	-0.455	-2.209	.003	.009	3	2
UCEC	14-3-3_beta →	-0.091	-3.780	.008	<.001	3	1
UCEC	EGFR_pY1068 →	-0.264	-2.137	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

eEF2 by ANKZF1 expression — UCEC

Explore this box plot interactively →