ANKS4B

Across TCGA pan-cancer cohorts, ANKS4B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ANKS4B data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ANKS4B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ANKS4B expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and COAD are the cancer types where ANKS4B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.745	0.394	<.001	59	view →
CCRCC	OS	Tertile	II,III,IV	1.000	0.713	.003	33	view →
COAD	DFS	Median	All	1.000	0.888	.023	30	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ANKS4B–PDAC (OS)

Open the PDAC breakdown →