ANKS3

Across TCGA patient cohorts, ANKS3 mutation is significantly associated with the RNA expression of many other genes, with 3,420 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS3-associated genes across cancer lineages are RN7SKP98, MIR4710, and RNU6-434P. Each is linked with ANKS3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKS3-to-partner and partner-to-ANKS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP98 grouped by ANKS3-low versus ANKS3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS3→partner) and Y-score (partner→ANKS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP98 →	+0.191	+2.357	.003	.003	3	3
CESC	MIR4710 →	+0.724	+5.539	<.001	.004	3	2
BLCA	RNU6-434P →	+0.188	+5.033	<.001	.003	3	2
HNSC	SNORD70B →	+0.534	+4.452	<.001	.006	3	2
CESC	CTSLP6 →	+0.056	+5.103	<.001	.008	3	2
CESC	TXNL4AP1 →	+0.129	+5.539	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,420 associations by consensus.

RN7SKP98 by ANKS3 expression — SKCM

Explore this box plot interactively →