ANKS1B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKS1B mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS1B-associated genes across cancer lineages are ASNS, Caspase-7-cleavedD198, and eEF2. Each is linked with ANKS1B in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKS1B-to-partner and partner-to-ANKS1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS1B→partner) and Y-score (partner→ANKS1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADASNS →+0.521+1.708<.001.02635
COADCaspase-7-cleavedD198 →+1.411+3.601<.001.00134
COADeEF2 →+0.284+3.459.011.00533
LUSCBim →+0.497+1.594<.001.02133
UCECATM →-0.482-2.649<.001<.00133
UCECCyclin-B1 →+0.399+1.206.009.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration