Across TCGA cell cohorts, ANKS1B mutation is significantly associated with the RNA expression of many other genes, with 562 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKS1B-associated genes across cancer lineages are CTC1, ZNF679, and MRAP. Each is linked with ANKS1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKS1B-to-partner and partner-to-ANKS1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS1B→partner) and Y-score (partner→ANKS1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CTC1 →	+0.685	+3.169	.002	.006	3	2
LIVER	ZNF679 →	+0.017	+3.662	.003	.005	3	1
UPPER_AERODIGESTIVE_TRACT	MRAP →	+0.028	+4.736	<.001	.009	3	1
LUNG_SCLC	RPL10L →	+1.066	+3.632	<.001	.003	3	1
LUNG_SCLC	OR13H1 →	+0.064	+3.502	<.001	.004	3	1
LUNG_SCLC	C8orf74 →	+0.062	+2.874	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 562 associations by consensus.

Exploration

ANKS1B survival (RNA) · tumor vs normal (RNA) · all ANKS1B data types