ANKS1A

Across TCGA patient cohorts, ANKS1A protein abundance is significantly associated with the RNA expression of many other genes, with 8,507 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANKS1A-associated genes across cancer lineages are RNF8, PBX2, and RNF5. Each is linked with ANKS1A in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKS1A-to-partner and partner-to-ANKS1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKS1A versus RNF8 in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS1A→partner) and Y-score (partner→ANKS1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RNF8 →	+0.485	+0.254	.004	.001	3	5
OV	PBX2 →	+0.517	+0.182	<.001	<.001	3	5
OV	RNF5 →	+0.461	+0.185	<.001	<.001	3	5
LUAD	PPP1R11 →	+0.379	+0.153	<.001	<.001	3	5
BRCA	TBC1D22B →	+0.465	+0.188	<.001	.002	3	5
OV	NELFE →	+0.636	+0.320	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,507 associations by consensus.

ANKS1A vs RNF8 — OV

Explore this scatter interactively →