ANKS1A

Across TCGA patient cohorts, ANKS1A mutation is significantly associated with the RNA expression of many other genes, with 5,250 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS1A-associated genes across cancer lineages are BTBD6, TLE6, and CXXC1. Each is linked with ANKS1A in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKS1A-to-partner and partner-to-ANKS1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD6 grouped by ANKS1A-low versus ANKS1A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS1A→partner) and Y-score (partner→ANKS1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BTBD6 →	+0.395	+3.223	.007	.008	3	3
BLCA	TLE6 →	+1.141	+3.329	.004	.005	3	3
UCEC	CXXC1 →	+0.263	+2.415	.008	.003	3	3
COAD	FAXDC2 →	-1.049	-3.687	<.001	.001	3	3
LUSC	RN7SL583P →	+0.284	+3.578	<.001	.002	3	3
UCEC	EIF2B2 →	+0.419	+1.710	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,250 associations by consensus.

BTBD6 by ANKS1A expression — COAD

Explore this box plot interactively →