ANKRD7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD7 mutation is significantly associated with the RNA expression of many other genes, with 1,858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD7-associated genes across cancer lineages are MIR6074, H3C1, and ZNF209P. Each is linked with ANKRD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD7-to-partner and partner-to-ANKRD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6074 grouped by ANKRD7-low versus ANKRD7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD7→partner) and Y-score (partner→ANKRD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR6074 →+0.307+7.731<.001.00932
UCECH3C1 →+0.886+2.180<.001.00232
COADZNF209P →+0.319+4.797<.001.00132
COADRNU6-694P →+0.896+5.478<.001<.00132
COADRNA5SP442 →+0.867+5.478<.001<.00132
COADKRTAP4-8 →+0.157+4.666.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,858 associations by consensus.

MIR6074 by ANKRD7 expression — BRCA

Box plot of MIR6074 in ANKRD7-low vs ANKRD7-high samples in BRCA.

Explore this box plot interactively →

Exploration