ANKRD7

Across TCGA patient cohorts, ANKRD7 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD7-associated genes across cancer lineages are ATM, FoxM1, and Notch1. Each is linked with ANKRD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD7-to-partner and partner-to-ANKRD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ANKRD7-low versus ANKRD7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD7→partner) and Y-score (partner→ANKRD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.543	-3.156	.002	.018	3	2
UCEC	FoxM1 →	+0.270	+2.415	.009	.003	3	1
UCEC	Notch1 →	+0.192	+2.469	<.001	.010	3	1
UCEC	p62 Lck ligand →	+0.399	+3.459	.002	.005	3	1
UCEC	PCNA →	+0.276	+2.415	.001	.003	2	2
UCEC	PDCD4 →	-0.523	-2.999	.005	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

ATM by ANKRD7 expression — UCEC

Explore this box plot interactively →