ANKRD7

Across TCGA cell cohorts, ANKRD7 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKRD7-associated genes across cancer lineages are OR10D3, TTLL8, and TBC1D21. Each is linked with ANKRD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD7-to-partner and partner-to-ANKRD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10D3 grouped by ANKRD7-low versus ANKRD7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD7→partner) and Y-score (partner→ANKRD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10D3 →	+0.034	+4.874	<.001	.002	3	2
LARGE_INTESTINE	TTLL8 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR10W1 →	+0.019	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.039	+4.273	<.001	.006	3	1
LARGE_INTESTINE	PFN3 →	+0.169	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OR10D3 by ANKRD7 expression — BLOOD_Leukemia

Explore this box plot interactively →