ANKRD7

Across TCGA cell cohorts, ANKRD7 mutation is significantly associated with the mutation status of many other genes, with 1,308 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD7-associated genes across cancer lineages are SGO2, TMPRSS11B, and NRXN2. Each is linked with ANKRD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD7-to-partner and partner-to-ANKRD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SGO2 grouped by ANKRD7-low versus ANKRD7-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD7→partner) and Y-score (partner→ANKRD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SGO2 →	+4.772	+5.339	.004	.004	1	3
LUNG_NSCLC_LUAD	TMPRSS11B →	+5.772	+5.772	.002	.002	1	3
SKIN	NRXN2 →	+2.807	+4.247	.007	.007	1	3
SKIN	UBXN11 →	+4.392	+4.392	.009	.009	1	3
LUNG_NSCLC_LUAD	IRAK3 →	+4.772	+5.339	.004	.004	1	3
BLOOD_Leukemia	BTBD9 →	+3.313	+3.430	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,308 associations by consensus.

SGO2 by ANKRD7 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →