ANKRD66

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD66 protein abundance is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD66-associated genes across cancer lineages are JAG1, RHOV, and CEACAM5. Each is linked with ANKRD66 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD66-to-partner and partner-to-ANKRD66 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD66 versus JAG1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD66→partner) and Y-score (partner→ANKRD66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECJAG1 →+0.583+1.293.004.00131
UCECRHOV →+1.368+1.222.009.00331
UCECCEACAM5 →+1.715+0.886.004.00531
UCECAGR2 →+2.251+1.314.009.00731
UCECAK1 →+0.646+1.205.009.00231
UCECTRIM16L →+0.624+1.002.008.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

ANKRD66 vs JAG1 — UCEC

Per-sample scatter of ANKRD66 vs JAG1 in UCEC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration