ANKRD63

Across TCGA patient cohorts, ANKRD63 protein abundance is significantly associated with the RNA expression of many other genes, with 719 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANKRD63-associated genes across cancer lineages are SEC14L2, SLC35E4, and PACSIN2. Each is linked with ANKRD63 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD63-to-partner and partner-to-ANKRD63 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD63 versus SEC14L2 in GBM, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD63→partner) and Y-score (partner→ANKRD63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC14L2 →	-1.034	-1.362	<.001	<.001	3	1
GBM	SLC35E4 →	-0.489	-1.283	.005	.001	3	1
GBM	PACSIN2 →	-0.604	-1.406	<.001	.001	3	1
GBM	CPNE6 →	+1.120	+0.916	<.001	.009	3	1
GBM	PXMP4 →	+0.464	+1.352	.003	.005	3	1
GBM	SLC32A1 →	+1.395	+1.473	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 719 associations by consensus.

ANKRD63 vs SEC14L2 — GBM

Explore this scatter interactively →