ANKRD60

Across TCGA cell cohorts, ANKRD60 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ANKRD60-associated genes across cancer lineages are HTR1E, LYZL2, and DEFB123. Each is linked with ANKRD60 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD60-to-partner and partner-to-ANKRD60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR1E grouped by ANKRD60-low versus ANKRD60-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD60→partner) and Y-score (partner→ANKRD60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HTR1E →	+0.036	+4.977	<.001	.007	3	1
LUNG_SCLC	LYZL2 →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	DEFB123 →	+0.103	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

HTR1E by ANKRD60 expression — SKIN

Explore this box plot interactively →