ANKRD60

Across TCGA cell cohorts, ANKRD60 mutation is significantly associated with the mutation status of many other genes, with 797 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD60-associated genes across cancer lineages are SUGP2, SPAG5, and GRM6. Each is linked with ANKRD60 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD60-to-partner and partner-to-ANKRD60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUGP2 grouped by ANKRD60-low versus ANKRD60-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD60→partner) and Y-score (partner→ANKRD60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SUGP2 →	+4.824	+5.392	.004	.004	1	3
SKIN	SPAG5 →	+4.824	+5.392	.004	.004	1	3
LARGE_INTESTINE	GRM6 →	+1.836	+2.906	.009	.009	1	3
LARGE_INTESTINE	PLEKHG4B →	+2.077	+3.129	.004	.004	1	3
LUNG_SCLC	HUWE1 →	+4.502	+5.066	.007	.007	1	2
LARGE_INTESTINE	ADAMTS2 →	+2.215	+3.247	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 797 associations by consensus.

SUGP2 by ANKRD60 expression — SKIN

Explore this box plot interactively →