ANKRD55

Across TCGA patient cohorts, ANKRD55 mutation is significantly associated with the RNA expression of many other genes, with 1,764 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD55-associated genes across cancer lineages are KCTD9, ITFG2, and DHDDS. Each is linked with ANKRD55 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD55-to-partner and partner-to-ANKRD55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCTD9 grouped by ANKRD55-low versus ANKRD55-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD55→partner) and Y-score (partner→ANKRD55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KCTD9 →	+0.686	+2.828	<.001	.001	3	3
UCEC	ITFG2 →	-0.337	-2.783	.004	.003	3	3
UCEC	DHDDS →	+0.329	+2.732	.002	.003	3	3
COAD	SOD1P1 →	+0.096	+3.051	.002	.003	3	2
COAD	GRPEL2P2 →	+0.103	+2.740	.002	.008	3	2
UCEC	DOC2A →	-0.595	-2.279	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,764 associations by consensus.

KCTD9 by ANKRD55 expression — UCEC

Explore this box plot interactively →